▶原著論文 Original article (2009~)

Ohhara, Y., Sagisaka, C., Yamakawa-Kobayashi, K. The collembolan Sinella dubiosa produces eicosapentaenoic acid. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 110900. Advance online publication (2023).

 

Sato M., Ota R., Kobayashi S., Yamakawa-Kobayashi K., Miura T., Ido A., Ohhara Y. Bioproduction of n-3 polyunsaturated fatty acids by nematode fatty acid desaturases and elongase in Drosophila melanogaster.
Transgenic Research. 10.1007/s11248-023-00363-9. Advance online publication (2023).

 

Ikeno R, Ohhara Y, Goda T, Yamakawa-Kobayashi K. Combined effect of genetic variations in the genes for HSP90/HSP70 families and lifestyle factors for determining metabolic parameters: A population based study,

Gene Reports. 31:101759 (2023).

 

Ohhara Y, Yamanaka N. Internal sensory neurons regulate stage-specific growth in Drosophila.

Development. 149:dev200440 (2022).

 

Ohhara Y, Kato Y, Kamiyama T, Yamakawa-Kobayashi K. Su(var)2-10- and Su(var)205-dependent upregulation of the heterochromatic gene neverland is required for developmental transition in Drosophila.

Genetics. 222:iyac137 (2022).

 

Yamakawa-Kobayashi K, Ishikawa S, Miyake N, Ohhara Y, Goda T. Influences of the interactions of genetic variations of seven core circadian clock genes with lifestyle factors on metabolic parameters.

Lifestyle Genomics. 15:124-130 (2022).

 

Ohhara Y, Hoshino G, Imahori K, Matsuyuki T, Yamakawa-Kobayashi K. The Nutrient-Responsive Molecular Chaperone Hsp90 Supports Growth and Development in Drosophila.
Front. Physiol. 12:922 (2021).

 

Sato A, Ohhara Y, Miura S, Yamakawa-Kobayashi K. The Presence of Odd-chain Fatty Acids in Drosophila Phospholipids.

Biosci. Biotechnol. Biochem. 84:2139-2148 (2020).

 

Imura E, Shimada-Niwa Y, Nishimura T, Hückesfeld S, Schlegel P, Ohhara Y, Kondo S, Tanimoto H, Cardona A, Pankratz M J. Niwa R. The Corazonin-PTTH Neuronal Axis Controls Systemic Body Growth by Regulating Basal Ecdysteroid Biosynthesis in Drosophila melanogaster.

Curr. Biol. S0960-9822:30420-6 (2020).

 

Yamakawa-Kobayashi K, Ohhara Y, Kawashima T, Ohishi Y, Kayashima Y. Loss of CNDP causes a shorter lifespan and higher sensitivity to oxidative stress in Drosophila melanogaster.
Biomed. Res. (Tokyo). 41:131-138 (2020).


Ohhara Y, Nakamura A, Kato Y, Yamakawa-Kobayashi K. Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila.
PLoS Genet. 15:e1008121 (2019).

 

Ohhara Y, Kobayashi S, Yamakawa-Kobayashi K, Yamanaka N. Adult-specific insulin-producing neurons in Drosophila melanogaster.
J. Comp. Neurol. 526:1351-1367 (2018).

 

Yamakawa-Kobayashi K, Otagi E, Ohhara Y, Goda T, Kasezawa N, Kayashima Y. The Combined Effects of Genetic Variation in the CNDP1 and CNDP2 Genes and Dietary Carbohydrate and Carotene Intake on Obesity Risk.
J. Nutrigenet. Nutrigenomics. 10:146-154 (2017).

 

Ohhara Y., Kobayashi S., Yamanaka N. Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster.
PLoS Genet. 13:e1006583 (2017).

 

Ohhara Y, Shimada-Niwa Y, Niwa R, Kayashima Y, Hayashi Y, Akagi K, Ueda H, Yamakawa-Kobayashi K, Kobayashi S. Autocrine regulation of ecdysone synthesis by beta3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis.
Proc. Natl. Acad. Sci. USA. 112:1452-7 (2015).

 

Goda N, Murase H, Kasezawa N, Goda T, Yamakawa-Kobayashi K. Polymorphism in microRNA-binding site in HNF1B influences the susceptibility of type 2 diabetes mellitus: a population based case-control study.
BMC Med. Genet. 16:75 (2015).

 

Kayashima Y, Murata S, Sato M, Matsuura K, Asanuma T, Chimoto J, Ishii T, Mochizuki K, Kumazawa S, Nakayama T, Yamakawa-Kobayashi K. Tea polyphenols ameliorate fat storage induced by high-fat diet in Drosophila melanogaster.
Biochem. Biophys. Rep. 4:417-424 (2015).

 

Inamori T, Goda T, Kasezawa N, Yamakawa-Kobayashi K. The combined effects of genetic variation in the SIRT1 gene and dietary intake of n-3 and n-6 polyunsaturated fatty acids on serum LDL-C and HDL-C levels: a population based study.
Lipids Health Dis. 12:4 (2013).

 

Kayashima Y, Sato A, Kumazawa S, Yamakawa-Kobayashi K. A heteroallelic Drosophila insulin-like receptor mutant and its use in validating physiological activities of food constituents.
Biochem. Biophys. Res. Commun. 434:258-262 (2013).

 

Waguri T, Goda T, Kasezawa N, Yamakawa-Kobayashi K. The combined effects of genetic variations in the GPR120 gene and dietary fat intake on obesity risk.
Biomed. Res. 34:69-74 (2013).

 

Shiotani S, Yanai N, Suzuki T, Tujioka S, Sakano Y, Yamakawa-Kobayashi K, Kayashima Y. Free Amino Acid Composition and Effect of a Dipeptide-enriched Diet in an Adult Drosophila melanogaster Laboratory Strain.
Biosci. Biotechnol. Biochem. 77:836-838 (2013).

 

Inoue H, Yamakawa-Kobayashi K, Suzuki Y, Nakano T, Hayashi H, Kuwano T. A case study on the association of variation of bitter-taste receptor gene TAS2R38 with the height, weight and energy intake in Japanese female college students.
J. Nutri. Sci. Vitaminol. 59:16-21(2013).

 

Yamakawa-Kobayashi K, Natsume M, Aoki S, Nakano S, Inamori T, Kasezawa N, Goda T. The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.
BMC Medical Genet. 13:11 (2012).

 

Ohhara Y, Kayashima Y, Hayashi Y, Kobayashi S, Yamakawa-Kobayashi K. Expression of beta-adrenergic-like octopamine receptors during Drosophila development.
Zoological Science 29:83-89 (2012).

 

Kayashima Y, Yamanashi K, Sato A, Kumazawa S, Yamakawa-Kobayashi K. Freeze-dried royal jelly maintains its developmental and physiological bioactivity in Drosophila melanogaster.
Biosci. Biotechnol. Biochem. 76:2107-2111 (2012).

 

Kayashima Y, Yamakawa-Kobayashi K. Involvement of Prx3, a Drosophila ortholog of the thiol-dependent peroxidase PRDX3, in age-dependent oxidative stress resistance.
Biomed. Res. 33:319-322 (2012).

 

Hiroi M, Nagahara Y, Miyauchi R, Misaki Y, Goda T, Kasezawa N, Sasaki S, Yamakawa-Kobayashi K. The combination of genetic variations in the PRDX3 gene and dietary fat intake contribute to obesity risk.
Obesity 19:882-887 (2011).

 

Tsuboi H, Sakakibara H, Yamakawa-Kobayashi K, Tatsumi A, Inamori T, Hamamoto R, Suzuki A, Shimoi K. Val1483Ile polymorphism in the fatty acid synthase gene was associated with depressive symptoms under the influence of psychological stress.
J. Affect. Disord. 134:448-452 (2011).

 

Osada K, Miyauchi R, Goda T, Kasezawa N, Horiike H, Iida M, Sasaki S, Yamakawa-Kobayashi K. Variations in the WNK 1 gene modulates the effect of dietary intake of sodium and potassium on blood pressure determination.
J Hum Genet. 54:474-478 (2009).